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Table 4 Presence of MAPK interaction motifs in the ETS family

From: Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells

ETS

Mean Rank

D Domain

FXF

FXFP

PX(S/T)P

SP/TP

ELK1

1.3

2

1

1

3

14

ETV3

2.7

4

3

1

2

12

ELK4

4.3

1

1

1

3

18

ETV5

5.0

3

0

0

3

6

ERF

6.0

2

5

2

7

18

ETV7

6.3

2

1

0

1

7

FEV

6.7

1

1

0

1

2

ELF2

9.7

4

0

0

1

16

SPIB

9.7

0

1

0

1

3

ETV6

11.7

3

1

0

2

16

ETV4

12.0

2

0

0

1

7

ETS1

12.3

3

0

0

0

4

ETS2

12.3

2

0

0

0

5

ETV1

14.0

3

1

0

2

6

ELK3

14.3

4

1

1

1

15

ELF4

14.7

4

0

0

1

8

SPDEF

16.3

2

0

0

1

8

ERG

16.3

2

1

1

0

10

SPI1

19.3

1

1

0

0

3

GABPA

20.3

2

0

0

0

2

ELF3

21.0

0

1

0

0

2

FLI1

21.0

2

0

0

0

4

ELF1

21.0

6

1

0

1

12

ELF5

24.0

0

0

0

0

1

EHF

24.7

2

1

0

0

1

ETV2

25.0

2

1

1

0

3

SPIC

26.0

1

1

0

0

2

  1. ETS proteins are listed by the mean ranking for ERK2, JNK1, and p38α from Tables 1, 2 and 3. The number of indicated motifs is listed. Sequence of D domains is detailed in (Additional file 4: Table S2).