Cell Communication and Signaling

Table 1 ERK2 kinase specificity in the ETS family

From: Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells

Protein	Score	Previous report
ELK1	22.7	Yang et al. [20]
ETV5	9.0	Janknecht et al. [21]
ERF	8.9	Le Gallic et al. [22]
ELK4	8.4	Strahl et al. [23]
ETV3	6.9	Carlson et al. [8]
ERG	2.0
FEV	1.3
ELK3	1.2	Ducret et al. [24]
SPIB	1.2	Mao et al. [25]
ETS1	1.0	Yang et al. [26]
ETS2	1.0	Yang et al. [26]
ETV7	0.8
ETV4	0.8	O’Hagan et al. [27]
ETV1	0.8	Janknecht [28]
ETV6	0.7	Maki et al. [29]
ELF4	0.7
GABPA	0.2	Flory et al. [30]
ELF2	0.2
ELF1	0.1
SPDEF	0.1
ELF3	0.1
FLI1	0
ELF5	0
ETV2	0
SPIC	0
SPI1	0
EHF	0

The phosphorylation score is the ratio of radiolabel to total protein normalized to ETS1. The third column references a previous report of in vitro phosphorylation by any member of the ERK MAPK family, if applicable.

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ISSN: 1478-811X

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