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Figure 3 | Cell Communication and Signaling

Figure 3

From: Non-canonical regulation of phosphatidylinositol 3-kinase gamma isoform activity in retinal rod photoreceptor cells

Figure 3

PI3K activity associated with CNGA1 is independent of light and IR activation. Solubilized ROS from either dark or light-adapted mice (A) or IR wild-type (C) or IR knockout (C) mice were immunoprecipitated with anti-CNGA1 antibody or non-immune IgG. PI3K activity was measured using PI-4,5-P2 and [γ32P]ATP as substrates. The radioactive spots of PI-3,4,5-P3 were scraped from the TLC plate and counted (B, D). Data are mean ± SD (n = 3).

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