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Figure 3 | Cell Communication and Signaling

Figure 3

From: A global microRNA screen identifies regulators of the ErbB receptor signaling network

Figure 3

Analysis of the screen data. (A) Screen hits depicted in list format. Mean values of the pAkt/Akt ratios for the basal and HRG-stimulated condition are shown, with green indicating a reduction and red an increase compared to the mean of miR-con (black). ΔpAkt values (mean of the two replicates) for each miRNA screen hit is shown as a bar chart. (B) miRNAs were clustered according to their seed region and for each miRNA ΔpAkt is visualized as a color-coded value. All seed families with more than 3 members are listed. Values correspond to the mean of the two replicates.

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