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Figure 2 | Cell Communication and Signaling

Figure 2

From: TNF-α and IGF1 modify the microRNA signature in skeletal muscle cell differentiation

Figure 2

Principal component analyses of miRNA in early skeletal myoblast differentiation and TNF-α or IGF1 treatment. Principal component analyses of murine miRNA expression profiling data after 24 h of induction differentiation and TNF-α or IGF1 treatment. Principal component analysis reveals separation of treatment groups for (A) microarray and (B) qPCR data. Dynamic principal component analysis (group selection myoblasts) identifies the most relevant subset of miRNAs which can describe the treatment effects and separate the effects by principal components for (C) microarray and (D) qPCR data. Axes depict principal component 1 (PC 1), principal component 2 (PC 2), and principal component 3 (PC 3).

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