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Table 3 Overview of the effect on nutrients in the integrative model

From: Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics

Effect

Free nutrients

Bound nutrients

Local increase of free nutrients

+

0

Global decrease of bound nutrients

0

-

Global conversion of free to bound nutrients

-

+

Lysosomal recycling

+

-

Autophagosomal uptake

0

-

Autolysosomal release

+

0

  1. (+) indicates an increase, (-) indicates a decrease, (0) indicates no change.