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Table 1 Ontology analysis of SDEG in mouse brain infected by wild type or Itr1aΔ itr3cΔ mutant cells

From: Cryptococcus inositol utilization modulates the host protective immune response during brain infection

  

Wild type

 

Itr1aΔ itr3cΔ

 

No.

Category

p value (range)

Number of genes

p value (range)

Number of genes

1

Neurological Disease

5.56E-61-6.96E-05

792

3.59E-37-9.9E-11

326

2

Cell Death and Survival

7.57E-30-1.19E-04

842

2.9E-45-9.82E-11

379

3

Cell-To-Cell Interaction

1.69E-28-1.02E-04

352

3.09E-42-1.3E-10

248

4

Nervous System Development and Function

1.69E-28-7.79E-05

663

2.11E-11-1.07E-10

108

5

Cellular Growth and Proliferation

2.12E-22-1.02E-04

794

1.6E-47-1.02E-10

381

6

Gene Expression

3.8E-19-7E-05

541

1.37E-15-3.02E-11

112

7

Cellular Movement

1.96E-09-1.2E-04

481

1.32E-58-1.3E-10

293

8

Cell Signaling

8.74E-05-8.74E-05

22

7.41E-18-4.05E-12

129

9

Cell-mediated Immune Response

ns

 

5.81E-17-3.17E-13

42

10

Humoral Immune Response

ns

 

9.21E-27-1.02E-10

102

11

Inflammatory Response

ns

 

2.72E-38-1.2E-10

90

12

Immune Cell Trafficking

ns

 

1.48E-46-1.3E-10

108

13

Antimicrobial Response

ns

 

2.21E-15-5.49E-12

212

14

Free Radical Scavenging

ns

 

1.05E-27-8.25E-11

304

  1. ns-not statistically significant.