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Figure 1 | Cell Communication and Signaling

Figure 1

From: Cryptococcus inositol utilization modulates the host protective immune response during brain infection

Figure 1

Summary of genome-wide transcriptome analysis of the wild type or itr1aΔ itr3cΔ mutant infected mouse brain. (A) Venn diagram showing the number of total and common SDEG dysregulated in the brain of mouse infected with the wild type H99 (red circle) or the itr1aΔ itr3cΔ mutant (blue circle). (B) Intensity plot of the SDEG from the wild type (H99)-infected, relative to the uninfected, animals. (C) Intensity plot of all the SDEG from the mutant-infected, relative to the uninfected, animals. The plots were drawn with descending level of gene expression (top to bottom). The scale bar ranges from +3 (red) to -3(blue) and is common to both (B) and (C). The RNA-seq data was obtained from 3 mouse per group and analyzed group-wise by one-way ANOVA (n = 3/group).

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