Figure 7
From: TCR-triggered extracellular superoxide production is not required for T-cell activation
NOX2 is not required for T-cell proliferation. (A) Splenic T cells from WT or gp91 phox−/− mice were loaded with CFSE and stimulated with CD3xCD28-coated microbeads. After 72 hours CFSE dilution was analyzed by flow cytometry. The data are representative of 2 independent experiments. 2 WT and 4 gp91 phox−/− mice were used in each experiment. (B) Quantification of (A). The values indicate the percentages of proliferating cells.