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Figure 6 | Cell Communication and Signaling

Figure 6

From: TCR-triggered extracellular superoxide production is not required for T-cell activation

Figure 6

NOX2 is not required for primary T-cell activation. (A) Splenic T cells from WT or gp91 phox−/− mice were stimulated with CD3xCD28-coated microbeads. After 16 hours cells were stained with CD25-FITC and CD69-PE mAbs and analyzed by flow cytometry. The data are representative of at least 2 independent experiments. 1 WT and 2 gp91 phox−/− mice were used in each experiment. (B) Quantification of (A). The values indicate the mean fluorescence intensities. (C) Quantification of (A). The values indicate the percentages of CD69+CD25+ cells.

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