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Figure 5 | Cell Communication and Signaling

Figure 5

From: The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2

Figure 5

High resolution FESEM of C. jejuni- induced filopodia formation and invasion. (A) Infection of GD25 knockout cells with wt C. jejuni 81-176 (yellow arrows) for 6 hours revealed bacterial attachment to the cell surface with short microspikes (green arrowheads) present, but membrane dynamics events or invasion were rarely seen. Similar observations were made with infected fibronectin-/- or FAK-/- cells. (B) Infecting C. jejuni in wt cells were regularly associated with long filopodia (blue arrows) membrane ruffling (red arrows), as well as elongated microspikes (green arrowheads).

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