Figure 3
From: PDZ domains and their binding partners: structure, specificity, and modification
The amino acid residues in the carboxylate-binding loop regions of PDZ domains adopt a specific conformation. (A) Selected 'X-Φ-G-Φ' motifs from known structures of PDZ domains, where X represents any amino acid residue and Φ represents hydrophobic amino acid residues. (B) 4 Top boxes: Distribution of the (ϕ,ψ) angle of the amino acid residue at the specific position. Bottom: Ribbon diagram of the Dvl1 PDZ domain (grey, PDB code: 2KAW); the X1-Φ2-G3-Φ4 motif is highlighted (stick).