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Figure 6 | Cell Communication and Signaling

Figure 6

From: The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

Figure 6

Kinetics of FRS2 phosphorylation induced by different concentration of FGF-2 Rama 27 fibroblasts were stimulated with the indicated doses of FGF-2 for 0 min to 180 min. Following pull down with p13 suc1, phosphorylated FRS2 was identified by Western blotting (WB) with the phosphotyrosine antibody 4G10 (see Methods). The same blots were re-probed with anti-FRS2 to show the levels of loading. Upper panel 0.3 ng/mL FGF-2; lower panel 100 ng/mL FGF-2.

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