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Figure 7 | Cell Communication and Signaling

Figure 7

From: Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture

Figure 7

Detection of phosphorylated (p)-MAPK44/42. (A) Western blots. There was a significant increase in the expression of p-MAPK44/42 in the UtLM/FB compared to cultures of UtLM cells or FB alone at 24 h, 48h and day 7. (B) Densitometry. There was a significant increase in the expression of p-MAPK44/42 in cocultured UtLM cells compared to non-cocultured UtLM cells and FB at 24 h (p < 0.0001), 48 h (p = 0.05) and day 7 (p = 0.05). There were no differences observed between the culturing conditions for total (t)-MAPK44/42 expression. All error bars represent SEM.

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