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Figure 6 | Cell Communication and Signaling

Figure 6

From: Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture

Figure 6

Expression of phosphorylated (p)RTKs. (A) pRTK array. The array detected activated RTKs for GFs under both culturing conditions (B) Densitometry. There was an overall increase in the expression of 5 pRTKs in the UtLM/FB compared to UtLM cells cultured alone. Significant (p = 0.02) increases in the phosphorylated receptors, ErbB4 and PDGFα/β, were found in the UtLM/FB compared to UtLM cells cultured alone. All error bars represent SEM.

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