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Table 3 Differential expression of selected genes in the ganglion cell layer 6 hrs after optic nerve injury

From: Early cellular signaling responses to axonal injury

   

Genbank

Fold

 

Group

Gene Symbol

Description

Accession

Change

p-value

Signal transduction

 

Socs3

Suppressor of cytokine signaling 3

BB241535

3.33

0.0018

 

Gsk3b

Glycogen synthase kinase 3 beta

BG063622

1.39

0.0454

 

Akap9

A kinase (PRKA) anchor protein 9

BB109183

1.59

0.0165

 

Pdgfra

Platelet derived growth factor receptor -alpha

AW537708

1.50

0.0325

 

IL20rb

Interleukin 20 receptor beta

BE852308

1.84

0.0371

 

Prkcbp1

Protein Kinase C binding protein 1

AK014397

1.36

0.0417

 

Mast2

Microtubule associated serine/threonine kinase 2

NM_008641

1.30

0.0319

 

Map3k10

Mitogen activated protein kinase kinase kinase 10

AI851771

-1.48

0.0363

Calcium tansport/homeostasis

     
 

Camk2a

Calcium/calmodulin-dependent protein kinase II alpha

AW490258

1.32

0.0245

 

Cacng2

Calcium channel, voltage-dependent, gamma subunit 2

BB342913

1.26

0.0298

 

Itpr2

Inositol 1,4,5-triphosphate receptor 5

BC013815

-1.44

0.0102

 

Trpc2

Transient receptor potential cation channel, subfamily C, member 2

BC003841

1.24

0.0318

 

Gcm2

Glial cells missing homolog 2

AF081556

1.37

0.0224

Cell Death

     
 

Bax

Bcl2-associated × protein

BC018228

1.32

0.0275

 

Faim3

Fas apoptotic inhibitory molecule 3

AK007714

-2.48

0.0118

 

Atf2

Activating transcription factor 2

BM119623

1.25

0.0489

 

Ercc1

Excision repair cross-complementing rodent repair deficiency1

AW538163

-1.27

0.0155

 

Foxp1

Forkhead box P1

BM220880

1.27

0.0285

 

Nfatc4

Nuclear factor of activated T-cells, calcineurin-dependent 4

AV166177

-1.65

0.0387

 

Rasa1

RAS p21 protein activator

AA124924

1.23

0.0390

 

Rtn4

Reticulon 4

BE988775

1.31

0.0187

 

Ski

v-Ski sarcoma viral oncogene homolog

AV381512

1.33

0.0371

 

Smad5

SMAD, mothers against DPP homolog 5

U77638

-1.7

0.0250

 

Aifm3

Apoptosis inducing factor, mitochondrion-associated 3

BF320633

1.31

0.0221