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Table 1 Gene Ontology Analysis of Phosphoproteins after Axonal Injury

From: Early cellular signaling responses to axonal injury

GO ID

Total

Under

Over

Change

p-Value

Term

166

2142

7

20

27

0.0001

nucleotide binding

17076

1853

7

15

22

0.0014

purine nucleotide binding

30554

1533

6

13

19

0.0019

adenyl nucleotide binding

5524

1446

6

12

18

0.0024

ATP binding

7242

1200

5

8

13

0.0278

intracellular signaling cascade

16301

951

4

8

12

0.0118

kinase activity

5198

807

2

9

11

0.0092

structural molecule activity

16773

770

2

8

10

0.0175

phosphotransferase activity, OH acceptor

4672

669

2

7

9

0.0194

protein kinase activity

6468

673

2

6

8

0.0498

protein amino acid phosphorylation

30001

406

2

5

7

0.0113

metal ion transport

15672

321

1

5

6

0.013

monovalent inorganic cation transport

5216

353

1

5

6

0.0197

ion channel activity

15268

386

1

5

6

0.029

alpha-type channel activity

15267

407

1

5

6

0.0361

channel or pore class transporter activity

9966

443

2

4

6

0.0508

regulation of signal transduction

6813

168

1

4

5

0.0035

potassium ion transport

7017

216

3

2

5

0.0098

microtubule-based process

5261

254

1

4

5

0.0186

cation channel activity

3779

259

1

4

5

0.02

actin binding

5516

111

1

3

4

0.0045

calmodulin binding

5267

140

0

4

4

0.0101

potassium channel activity

3712

160

2

2

4

0.0158

transcription cofactor activity

5244

175

1

3

4

0.0212

voltage-gated ion channel activity