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Table 1 Gene Ontology Analysis of Phosphoproteins after Axonal Injury

From: Early cellular signaling responses to axonal injury

GO ID Total Under Over Change p-Value Term
166 2142 7 20 27 0.0001 nucleotide binding
17076 1853 7 15 22 0.0014 purine nucleotide binding
30554 1533 6 13 19 0.0019 adenyl nucleotide binding
5524 1446 6 12 18 0.0024 ATP binding
7242 1200 5 8 13 0.0278 intracellular signaling cascade
16301 951 4 8 12 0.0118 kinase activity
5198 807 2 9 11 0.0092 structural molecule activity
16773 770 2 8 10 0.0175 phosphotransferase activity, OH acceptor
4672 669 2 7 9 0.0194 protein kinase activity
6468 673 2 6 8 0.0498 protein amino acid phosphorylation
30001 406 2 5 7 0.0113 metal ion transport
15672 321 1 5 6 0.013 monovalent inorganic cation transport
5216 353 1 5 6 0.0197 ion channel activity
15268 386 1 5 6 0.029 alpha-type channel activity
15267 407 1 5 6 0.0361 channel or pore class transporter activity
9966 443 2 4 6 0.0508 regulation of signal transduction
6813 168 1 4 5 0.0035 potassium ion transport
7017 216 3 2 5 0.0098 microtubule-based process
5261 254 1 4 5 0.0186 cation channel activity
3779 259 1 4 5 0.02 actin binding
5516 111 1 3 4 0.0045 calmodulin binding
5267 140 0 4 4 0.0101 potassium channel activity
3712 160 2 2 4 0.0158 transcription cofactor activity
5244 175 1 3 4 0.0212 voltage-gated ion channel activity