Figure 3From: Expression of excess receptors and negative feedback control of signal pathways are required for rapid activation and prompt cessation of signal transductionNegative feedback regulation of the signal pathways. I. The protein amounts and reaction probabilities were set as described in Additional file 1 and 2, respectively. L was added immediately before the 1.2 × 106th step (down arrow, 24 seconds) and removed after the 1.2 × 107th step (upper allow, 240 seconds), as described in the legend of Figure 2. Three simulation results are represented. II. Models for negative feedback regulation used in this study.Back to article page