Table 1 Summary of the effects of leptin and adiponectin on migration and proliferation of various cancer cell lines
From: Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration
| Â | Breast Carcinoma Cells | Colon Carcinoma Cells | ||
|---|---|---|---|---|
| Â | MCF-7 | MDA-MB-468 | MDA-MB-231 | SW480 |
Receptor expression | ||||
ObRI | + | + | + | + |
AdipoR1 | + | + | + | + |
AdipoR2 | + | + | + | + |
Migration | ||||
Leptin | no | no | no | + |
Adiponectin | no | no | no | + |
Leptin+Adipo. | no | no | no | - |
Proliferation | ||||
Leptin | +19% | +10% | +44% | +52% |
Adiponectin | +25% | +18% | +46% | -31% |
Leptin+Adipo. | +16% | +5% | +61% | +11% |