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Figure 5 | Cell Communication and Signaling

Figure 5

From: Function, regulation and pathological roles of the Gab/DOS docking proteins

Figure 5

The Phosphomaps of human Gab1 and Gab2. This cartoon is based on information from sources cited in the main text and on the Phosphosite homepage http://www.phosphosite.org. Phosphotyrosine residues involved or strongly implicated in the recruitment of the SH2 domain containing effectors Shp2, p85, Crk and PLCγ are indicated. Ser/Thr-residues phosphorylated in an ERK- or PI3K-dependent manner are also shown.

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