Skip to main content


Figure 1 | Cell Communication and Signaling

Figure 1

From: The small GTPase RhoH is an atypical regulator of haematopoietic cells

Figure 1

Alignment of the most prominent human Rho GTPases. RhoA, Rac1, Cdc42 and RhoH were aligned using the ClustalW alignment program [71]. Conserved residues are presented in red and RhoH specific amino acids are depicted in blue. The ITAM-like motif in RhoH comprising the sequence YxxA(X)6YxxA is underlined. Gray-shaded boxes mark the phosphate-binding loop, and switch I and switch II regions, respectively. The Rho family specific insertion motif that is absent in the other members of the Ras superfamily, is shown in bold typing.

Back to article page