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Table 1 Types of endothelium

From: Extravasation of leukocytes in comparison to tumor cells

Tissue

Type of endothelium

Adhesion molecules

Site of extravasation

Lung

non-fenestrated, continuous

minor role of selectins

microvasculature

Liver

discontinous, fenestrated

minor role of selectins, adhesion to exposed ECM

microvasculature

Lymph organs

HEV, plump und cuboidal

constitutive expression of L-selectin ligands

postcapillary venules, constitutive

Skin

non-fenestrated, continuous

adhesion molecules upregulated in case of inflammation

postcapillary venules

Blood/brain barrier

non-fenestrated, continuous

 

no regular extravasation