Table 4 Kinases (mouse) that do not have an FXFP motif and/or D-domain sequence. Kinases that use phosphatidylinositols or inositols as substrates and do not contain an FXFP or D-domain sequence are listed in the table; all sequences are for mouse proteins. The number of potential MAPK phosphorylation sites and sequences fitting the optimal MAPK phosphorylation in these kinases are also identified.
Isozyme | GenBank Accession # | # amino acids | # (S/T)P sites | Site(s) with the consensus PX(S/T)P sequence |
|---|---|---|---|---|
PI 3-kinase β | NP_083370 | 1064 | 4 | none |
PI 3-kinase δ | NP_032866 | 1043 | 3 | none |
PI 4-kinase type II-β (PI4K55) | NP_083020 | 445 | 2 | none |
PIP kinase Type Iiα | NP_032871 | 405 | 4 | 314PDSP |
PIP kinase Type Iiβ | Q80XI4 | 416 | 3 | 324PDSP |
PIP kinase Type Iiγ | NP_473438 | 421 | 2 | none |
Ins(1,4,5)P3 3-kinase A | Q8R071 | 459 | 5 | 18PCSP 92PASP |
Ins(1,4,5)P3 3-kinase C | NP_853624 | 678 | 8 | 328PETP |
Ins(1,3,4)P3 5/6-kinase/Ins(3,4,5,6)P4 1-kinase | NP_766172 | 419 | 4 | none |
Inositol polyphosphate multikinase/Ins(1,3,4,6)P4 5-kinase | Q7TT16 | 396 | 2 | none |