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Figure 1 | Cell Communication and Signaling

Figure 1

From: Identification of mitogen-activated protein kinase docking sites in enzymes that metabolize phosphatidylinositols and inositol phosphates

Figure 1

A: Pathways of metabolism of phosphatidylinositols in animals. This figure is based on similar figures in Toker [28] and Parker [29] and information provided in the Results and Discussion section. We are not aware of evidence that PtdIns5P is a substrate for a PI 3-kinase, producing PtdIns(3,5)P2; therefore, an arrow has not been included for this reaction.

B: Pathways of inositol phosphate metabolism. The pathways of the metabolism of inositol phosphates in animal cells are shown; additional pathways are present in plants and slime mold [30]. The PLC-catalyzed synthesis of 1,2-diacylglycerol (1,2-DAG) and Ins(1,4,5)P3 is also shown. The figure is based on similar figures found in Irvine and Schell [30], Shears [36], and Irvine [37], as well as information provided in the Results and Discussion section.

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Cell Communication and Signaling

ISSN: 1478-811X