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Figure 2 | Cell Communication and Signaling

Figure 2

From: Comparable response of ccn1 with ccn2 genes upon arthritis: An in vitro evaluation with a human chondrocytic cell line stimulated by a set of cytokines

Figure 2

Coordinative repression and induction of ccn1 and ccn2 transcripts in response to inflammatory TNF-α (A) and pro-inflammatory TGF-β (B) in chondrocytic HCS-2/8 cells. Results of mRNA quantification by real-time RT-PCR analysis are displayed. Plotted values represent relative mRNA copy numbers versus those at time 0. Each copy number was computed by standardizing the raw data against those of β-actin. Open circles, ccn1; solid circles, ccn2. Mean values and standard deviations (SDs) of at least 2 experiments are shown.

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