Skip to main content
Figure 1 | Cell Communication and Signaling

Figure 1

From: Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells

Figure 1

Expression of CCN2/CTGF mRNA in sparse and confluent MPL cultures (in situ hybridization) with or without TGF-β stimulation. MPL cultures in the sparsity phase (A and B) and confluence phase (C and D) were treated with TGF-β (B and D) or PBS (control: A and C). The cells were then cultured for 12 hrs, fixed, and hybridized with an antisense riboprobe for ccn2/ctgf mRNA. CCN2/CTGF mRNA was distinctly expressed in the cells in the sparse (A), but not in those in the confluent (C) state. However, the addition of TGF-β enhanced the level of CCN2/CTGF mRNA strongly, not only in the sparse cultures (B), but also in the confluent ones (D).

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X