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Table 4 p38 MAP kinase activating agents in prostatic cells

From: Mitogen Activated Protein kinase signal transduction pathways in the prostate

Agent

Cell line

Apoptosis

Ref

FGF-1

DU145

?

79

FGF-2

DU145

?

79

Keratinocyte growth factor (FGF-7)

DU145

?

79

IL-6

LNCaP

?

13

TGF-β

PC3

+

87

Adenosine triphosphate

1E8, 2B4

?

25

Neu differentiation factor (NDF)/Heregulin

LNCaP

?

81

Vitamin D

LNCaP

?

47

Selenite

DU145

?

104

Arsenic trioxide

DU145, PC3

-

114

PEITC

PC3

-

46

Tyrphostin AGE82

LNCaP

+

18

FTY720

DU145

-

84

Phorbol esters

LNCaP

+

82