Figure 5

Model validation: intracellular pathway perturbation. A). pERK dose response curve at 10 min post ligand stimulation for simultaneous addition of FGF2 ligand and MEKi model prediction compared to experimental validation. B). pERK dose response curve at 10 min post ligand stimulation for MEKi addition 5 min post FGF2 ligand stimulation model prediction compared to experimental validation.