2D Clinostat | Random positioning machine | |||||
---|---|---|---|---|---|---|
Factor | LDD (pg/mL) | 72 h 1g (pg/mL) | 72 h s-μg (pg/mL) | LDD (pg/mL) | 72 h 1g (pg/mL) | 72 h s-μg (pg/mL) |
GM-CSF | 3.2 | 1536 ± 166 | 1172 ± 31* | 9.3 | 46.8 ± 6.9 | 110.8 ± 12.0* |
IFN-γ | 0.49 | n.d. | n.d. | 0.58 | n.d. | n.d. |
IL-2 | 1.0 | 1.9 ± 0.33 | n.d. | 2.6 | n.d. | n.d. |
IL-3 | 1.1 | n.d. | n.d. | 2.0 | n.d. | n.d. |
IL-4 | 4.4 | n.d. | n.d. | 3.2 | n.d. | n.d. |
IL-5 | 1.0 | n.d. | n.d. | 0.73 | n.d. | n.d. |
IL-6 | 0.84 | 282 ± 37 | 204 ± 17* | 0.85 | 43.8 ± 8.4 | 70 ± 15.6* |
IL-7 | 2.1 | n.d. | 2.1 ± 0.3 | 5.5 | n.d. | n.d. |
IL-8 | 0.63 | 7604 ± 410 | 5586 ± 267* | 0.49 | 226 ± 31 | 350 ± 36* |
IL-10 | 1.1 | n.d. | n.d. | 1.5 | n.d. | n.d. |
IL-18 | 3.7 | n.d. | n.d. | 3.2 | n.d. | n.d. |
MIP-1α | 8.2 | 3086 ± 390 | 2198 ± 379* | 6.0 | 113 ± 18 | 137 ± 24 |
MIP-1β | 4.0 | 261 ± 46 | 166 ± 28* | 4.6 | n.d. | n.d. |
MCP-1 | 4.6 | 47 ± 6 | 40 ± 3 | 4.9 | n.d. | n.d. |
TNF-α | 2.9 | 8.9 ± 1.2 | 7.0 ± 1.3 | 3.1 | n.d. | n.d. |
TNF-β | 2.3 | 2.3 ± 0.4 | n.d. | 4.4 | n.d. | n.d. |
BDNF | 3.0 | 20 ± 1.7 | 16 ± 1.7* | 6.2 | 41.2 ± 4.6 | 76.6 ± 4.7* |
Eotaxin-1 | 3.7 | 11.8 ± 1.8 | 12.4 ± 2.3 | 13 | 75.4 ± 9.9 | 99.4 ± 9.8* |
ICAM1 | 270 | 360 ± 74 | 350 ± 73 | 620 | 1328 ± 274 | 1840 ± 150* |
IL-1α | 0.24 | n.d. | n.d. | 0.19 | 0.85 ± 0.11 | 1.60 ± 0.29* |
IL-1β | 0.3 | n.d. | n.d. | 0.25 | 1.14 ± 0.22 | 2.02 ± 0.34* |
IL-1ra | 8.7 | n.d. | n.d. | 14 | 127 ± 38 | 226 ± 24* |
IL-12p40 | 16 | n.d. | n.d. | 17 | 128 ± 21 | 206 ± 29* |
IL-12p70 | 4.8 | 7.8 ± 0.6 | 7.3 ± 0.9 | 4.5 | 36.0 ± 4.2 | 46.2 ± 6.1 |
IL-15 | 39.0 | n.d. | n.d. | 41 | 142 ± 27 | 208 ± 28* |
IL-17 | 0.51 | 1.14 ± 0.32 | 1.0 ± 0.16 | 0.6 | 2.5 ± 0.4 | 4.5 ± 0.6* |
IL-23 | 51 | n.d. | n.d. | 69 | 590 ± 117 | 868 ± 78* |
MMP-3 | 5.8 | 260 ± 22 | 256 ± 19 | 7.4 | 51.2 ± 11.3 | 90.8 ± 11.1* |
SCF | 13 | 24 ± 4 | 19 ± 2 | 9.0 | 59.0 ± 16.1 | 94.6 ± 11.5* |
VEGF | 1.4 | 3062 ± 539 | 2814 ± 309 | 4.2 | 6048 ± 791 | 5044 ± 677 |