Figure 7
PGE 2 -dependent effect on β-catenin expression in Wnt-activated NE-4C cells. Western blot analysis was used to determine two forms of active β-catenin: non-phospho-(active) β-catenin (Ser33/37/Thr41) and phospho-β-catenin (Ser552) (92 kDa). (A) The expression of active β-catenin represented in fold change was 1, 2.09, 1.61, and 1.98, respectively. The error bars represent + SEM and values were considered significantly different from control at *p < 0.05. Only PGE2 + WntA condition was significantly different from WntA only condition. (B) There was no significant difference in phospho-β-catenin (Ser552) expression between the conditions. Average measurements represent protein from three independent experiments (N = 3). β-Actin was used to indicate equal loading.