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Figure 3 | Cell Communication and Signaling

Figure 3

From: The cell-to-cell coordination between activated T cells and CpG-stimulated macrophages synergistically induce elevated levels of IL-10 via NF-κB1, STAT3, and CD40/CD154

Figure 3

CD3/28/CpG induces IL-10 production in both macrophages and CD4+T cells. (A) Diagram of FACS analysis. (B, C) Splenocytes left untreated or treated with CpG, CD3/CD28, CD3/CD28/CpG for 72 hours and number of CD4 (B) or F4/80 (C) were measured via FACS. (C, D) Median fluorescence intensity of IL10 in the CD4+(D) or F4/80+(E) gated cells. *, P <0.05. N = 3.

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Cell Communication and Signaling

ISSN: 1478-811X