Figure 8From: C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesionAbi1, Cbl and p130Cas contribute to FA regulation. (A) Representative Western blots showing the expression and phosphorylation (p) of the indicated proteins in K562 cells upon knock-down of Cbl (clone 1), Abi1 (clone 2) or p130Cas (clone 5), and their corresponding control cells (see Figure 3). ß-actin was used as loading control. Relative ratios between the levels of the different analyzed proteins and ß-actin are shown. (B) The histograms represent the relative values of the levels of expression of the analyzed proteins relative to ß-tubulin. shCT-sc: Control shRNA from Santa Cruz Biotech., shCT-sg: Control shRNA from Sigma. Susp: suspension; FN: fibronectin.Back to article page