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Figure 8 | Cell Communication and Signaling

Figure 8

From: C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion

Figure 8

Abi1, Cbl and p130Cas contribute to FA regulation. (A) Representative Western blots showing the expression and phosphorylation (p) of the indicated proteins in K562 cells upon knock-down of Cbl (clone 1), Abi1 (clone 2) or p130Cas (clone 5), and their corresponding control cells (see Figure 3). ß-actin was used as loading control. Relative ratios between the levels of the different analyzed proteins and ß-actin are shown. (B) The histograms represent the relative values of the levels of expression of the analyzed proteins relative to ß-tubulin. shCT-sc: Control shRNA from Santa Cruz Biotech., shCT-sg: Control shRNA from Sigma. Susp: suspension; FN: fibronectin.

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