Skip to main content
Figure 4 | Cell Communication and Signaling

Figure 4

From: C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion

Figure 4

C3G, Cbl, Abi1, p130Cas and p38α MAPK regulate adhesion to fibronectin in K562 cells. (A) Percentage of adhesion to fibronectin of K562 cells upon knock-down of C3G (shC3G-1 and shC3G-8), Cbl (shCbl-1), Abi1 (Abi1-2) or p130Cas (shp130Cas-5). (B) Percentage of adhesion to fibronectin of K562 clones expressing interference RNAs (cloned in pSuper.gfp/neo) for C3G and/or p38α MAPK. The values are the mean ± SEM of at least three independent experiments. All values are relative to K562 cells transfected with control shRNA or empty pSuper.gfp/neo vector (pSuper). *p<0.05; ** p<0,01.

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X