From: The effects of CA IX catalysis products within tumor microenvironment
Relative contribution of bicarbonate in DU145 growth rate increase in co-culture (%) | |
5% CO 2 + 10 mM HCO 3 - | |
pH 6.8 | 82% |
pH 7.4 | 100% |
pH 8.0 | 89% |
Relative contribution of bicarbonate in PC3 growth rate increase in co-culture (%) | |
5% CO 2 + 10 mM HCO 3 - | |
pH 6.8 | 1% |
pH 7.4 | 25% |
pH 8.0 | 38% |