Figure 3
From: Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling
Metastatic PR9692 cells adopted the amoeboid mode of invasion while non-metastatic PR9692-E9 cells use the mesenchymal mode. (A) 3D in vitro collagen invasion. (B) Immunochemical detection of MT1-MMP (MMP14) protein levels. (C) Activity of MMP-2 metalloproteinase detected by gelatin zymography.