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Figure 1 | Cell Communication and Signaling

Figure 1

From: Phosphodiesterase activity is regulated by CC2D1A that is implicated in non-syndromic intellectual disability

Figure 1

In vitro-binding of CC2D1A to PDE4D5. A. Schematic diagram of GST-CC2D1A and GST-PDE4D5 fusion constructs. B. Western blot of in vitro binding assays of recombinant proteins CC2D1A (fragments I, III, VII and GST) and recombinant PDE4D5 (fragment IX) probed with anti-PDE4D (upper panel) or anti-GST (middle panel and lower panel). The “Input” was purified recombinant PDE4D5 (fragment IX). C. Western blot of in vitro binding assays of recombinant proteins CC2D1A (fragments I and II) and recombinant PDE4D5 (fragment IX) probed with anti-PDE4D (upper panel) or anti-GST (middle panel and lower panel).

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