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Figure 2 | Cell Communication and Signaling

Figure 2

From: Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling

Figure 2

A comparison between experimental data (A, B) and simulated responses (C, D). (A, C): Flash responses generated by a dark-adapted toad rod over 5 orders of magnitude in light stimulus as a 24 ms flash, ranging in intensity from 1.5 R* per flash to 118,000 R* per flash. (B, D): Responses from a newt rod for 60 s steps of light ranging from 5 R* to 220,000 R*. Black traces are from the model of Dell’Orco & Koch (2011; ref. [19]); red dashed traces are from the present model. The two models do not vary greatly from each other for flash responses. When subjected to steps of light, the present model saturates at lower stimuli than the previous models and, in this regard, is more similar to the experimental data.

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