LPA-induced migration and invasion of EOC cells was reduced by YAP-siRNA. A, Reduced YAP expression by YAP siRNA in OVCA433 and OVCAR5 cells detected by Western blot. B and C, The effect of down-regulation of YAP on cell migration and invasion induced by LPA (10 μM) in OVCA433 and OVCAR5 cells (conducted 48 hr-post siRNA treatment). The results are from three independent experiments. ** P < 0.01.