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Table 1 Overview secreted cytokines, chemokines and growth factors by different polarized macrophages

From: Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts

 

Secreted factors by macrophages (pg/ml)

Ratio

Protein symbol

M1

M2

Unst.

M1:M2

M1:Unst.

M2:Unst

CCL2

743 ± 123

0

0

743

743

1

CCL3

45 ± 28

0

0

45

45

1

CCL4

192 ± 59

0

0

192

192

1

CCL5

26 ± 9

0

0

26

26

1

CCL18

37 ±19

64 ± 4

0

−2

37

64

CXCL9

183 ± 80

0

0

183

183

1

CXCL10

370 ± 83

7,4 ± 1,9

7,4 ± 1,2

50

50

1

FGF2

1,6 ± 3,2

10 ± 4

0

−6

1

10

IL6

31 ± 7

0

0

31

31

1

IL8

1171 ± 388

52 ± 11

63 ± 19

23

19

1

IL12p40/p70

84 ± 30

0

0

84

84

1

IL15

40 ± 11

0

0

40

40

1