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Figure 1 | Cell Communication and Signaling

Figure 1

From: Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms

Figure 1

Constitutively active mutants of G q family members stimulate PKD1 phosphorylation. HEK293 cells were transfected with pcDNA3, wild type (WT) or constitutively active (RC or QL) Gα subunits of Gq, G12, Gi and Gs families. Transfectants were then lysed, and proteins were subjected to SDS-PAGE and immunoblotting with antibodies against phospho-PKD1, PKD1, and specific Gα subunits.

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