The ARTD10 region spanning amino acids 600–868 contain additional element(s) that control subcellular localization. A. GFP-ARTD10 and GFP-ARTD10ΔNES were expressed transiently in COS7 cells. The cells were treated with or without LMB for 2 h. The subcellular distribution of the fusion proteins was measured by confocal microscopy. B. Identical experimental set-up for the indicated fusion proteins as in panel A. NLS, the nuclear localization sequence of the large T antigen of simian virus 40.