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Figure 8 | Cell Communication and Signaling

Figure 8

From: Identification of a potent serum factor that causes desensitization of the receptor for C-Type natriuretic peptide

Figure 8

S1P potently desensitizes GC-B in human aortic smooth muscle cells. A, cells were incubated with 100 nM S1P for 30 min and the responses to the indicated concentrations of CNP determined as described under Methods. B, cells were incubated for 30 min with the indicated concentrations of S1P or LPA as indicated and the responses to 20 nM CNP determined as described under Methods. Results are expressed as the mean of duplicate observations -/+ the range of duplicates.

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