Skip to main content
Figure 2 | Cell Communication and Signaling

Figure 2

From: Identification of a potent serum factor that causes desensitization of the receptor for C-Type natriuretic peptide

Figure 2

Low serum from a variety of species desensitizes GC-B to CNP. GCB/3T3 cells were incubated with heat-inactivated serum from the indicated species for 30 min prior to adding 0.25 mM IBMX and 20 nM CNP and cGMP contents were determined after 5 min of incubation with CNP as described under Methods. Error bars indicated the range of duplicate determinations.

Back to article page